With a slightly more complicated cell neighbourhood and switching rule -- Rule
While we are revising the genes of Conus shells we need to do something about their venom. They secrete a blend of simple peptide conotoxins which target multiple neurotransmitter pathways to anesthetise and tranquilise their victims. The blend varies from species to species, and within each species, their genes reshuffling to come up with new neurotoxins each season. As any fule kno, Olivera and Cruz (2001) introduced the term "nirvana cabal":
Yet there are surprisingly few records of recreational use! Pet cone-shells are not yet a hipster / druggie accoutrement. Perhaps it is the lack of a standard, predictable dose; perhaps it is the high fatality rate after cone-shell envenomation.
Conchopharmacologists have been promising the immanent arrival of medically-useful conotoxins, Just Around the Next Corner, for a couple of decades now, but so far the only one approved is synthetic ω-conotoxin as a painkiller... one with limited applications (because it must be injected directly into the
If truth were known, researchers only continue to analyse and catalog the different conotoxins because it gives them an excuse to 'milk' the molluscs into condoms:
...which is great to talk about when people ask what you do for a job.
UPDATE: Must belatedly recognise B4's journalistic priority in cone-shell toxicology and taxonomy.
Perhaps it is the lack of a standard, predictable dose; perhaps it is the high fatality rate after cone-shell envenomation.
ReplyDeleteThat's not going to stop any Floridian worth his salt. It might be the resulting having your face eaten rather than eating someone else's face that accounts for its lack of appearance on novelty drug shelves in the southeast US.
With a slightly more complicated cell neighbourhood and switching rule -- Rule 34 110 in Wolfram's catalog -- the diagonal stripes decorating the shells would cancel or cross when they meet in a way that is Turing-complete, i.e. the shells would be universal computers.
ReplyDeleteComputer shells, deadly toxins... RUH-ROH! Cones are drones!!!!
Also... cone shell toxins and condoms in science...
ReplyDeleteWhoops; note added to recognise B^4's priority in cone-shell-toxin blogging.
ReplyDeleteWill the Pope condone condom use by cone shells?
ReplyDelete~
+1 for Laundry reference.
ReplyDelete